Controlling Helix Handedness in Water-Soluble Quinoline Oligoamide Foldamers
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چکیده
منابع مشابه
Helix handedness inversion in arylamide foldamers: elucidation and free energy profile of a hopping mechanism.
We report the first atomistic level description of the handedness inversion mechanism for helical arylamide foldamers. The key process in the handedness inversion is the simultaneous unfolding and folding of two adjacent aryl-aryl linkages, propagating from a helix terminus along the strand. Intermediates along the inversion pathway have a common feature - a single unfolded aryl-aryl linkage (t...
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2014
ISSN: 1434-193X
DOI: 10.1002/ejoc.201402247